A potent chemical that is formed in the blood which causes surrounding muscles of the blood vessels to contract which narrows the vessels are called Angiotensin 11. Once narrows, the pressure in the vessels increases that causes hypertension or high blood pressure. ARBs or Angiotensin 11 receptor blockers are medicines that work by blocking the action of angiotensin 11 to bind to angiotensin 11 receptors on the surrounding blood vessels of the muscles. This can lead to enlarged blood vessels (dilated) which can thereby reduce blood pressure. When the blood pressure is reduced it aids the heart not to work hard to pump blood. This can help improve heart failure. ARBs may have a similar effect like ACE inhibitors but the latter works by preventing angiotensin 11 formation and not blocking the angiotensin 11 binding to muscles of the blood vessels.

Uses of ARBs

The medicines are used to normalize blood pressure, kidney failure prevention to patients with diabetes, and heart failure treatment. It may also prevent the risk of having diabetes and can even reduce stroke in patients with enlarged heart and hypertension. Recurrence of atrial fibrillation can also be prevented by taking ARBs.

Considering the similar effect of ACE inhibitors, this medicine is often prescribed to those who cannot tolerate the use of ACE inhibitors, for instance having an excessive cough.

Side effects

– Hyperkalemia or elevated level of potassium

– A cough (less often to occur than with ACE inhibitors)

– Dizziness

– Low blood pressure

– Diarrhea

– Drowsiness

– A headache

– Metallic or salty taste

– Orthostatic hypotension

– Rashes

– Indigestion

– Fatigue

– Increased level of blood glucose

– Sinusitis

– Flu-like symptoms

– Upper respiratory tract infection

– Bronchitis

There are also times when serious side effects may be experienced like hepatitis, kidney failure, decreased WBC (white blood cells) and blood platelets, serious allergic reactions, and tissue swelling.

Read here to learn more.

  1. October 31, 2018

    Angiotensin II receptor blockers (ARBs) are medications that block the action of angiotensin II by preventing angiotensin II from binding to angiotensin II receptors on the muscles surrounding blood vessels. As a result, blood vessels enlarge (dilate) and blood pressure is reduced.

  2. November 18, 2018

    Angiotensin II receptor blockers (ARBs) are used to treat conditions such as high blood pressure and heart failure. Angiotensin II receptor blockers help relax your blood vessels, which lowers your blood pressure and makes it easier for your heart to pump blood. It also reduces the amount of water your body retains, which lowers your blood pressure.

  3. November 27, 2018

    By experts opinion that Angiotensin receptor blockers (ARBs) lower your blood pressure by blocking the actions of angiotensin II. This allows your blood vessels to relax and widen, making it easier for blood to flow through. It also reduces the amount of water your body retains, which lowers your blood pressure. Thank you so much and keep posting things like this.

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