The generic name of imbruvica is ibrutinib. This is a medicine used to treat cancer. It works by interfering the development and spread of cancer cells in the body.

The drug was made to treat some types of cancers like non-Hodgkin lymphoma (Waldenstrom’s macroglobulinemia, MCL or mantle cell lymphoma and SLL small lymphocytic/CLL chronic lymphocytic leukemia. This can also be used for the treatment of chronic graft versus host disease and marginal cell lymphoma. It may be prescribed to patients once the other drugs used are no longer effective.

The US Food and Drug Administration also approved imbruvica to treat marginal lymphomas and mantle cell when used on an accelerated basis. Clinical studies showed that the drug is able to improve the symptoms and at times prolong the survival of the patients.

Things to remember

The medicine makes it easier for patients to bleed. For any unusual bleeding, it is advisable to contact the healthcare provider right away. Internal bleeding in the intestines or stomach and even the brain may also occur.

Speech problems, headache, confusion, dizziness, bloody stools, coughing of blood are among the symptoms of internal bleeding. All these should be reported to the physician immediately.

Before taking the medicine

It is best to check allergies. Also, the doctor needs to be notified if any of these diseases exist:

* Surgery

* Heart rhythm disorder

* Kidney or liver disease

* Blood clotting or bleeding issues

* Any active infection

* Surgery

* Any risk factor to develop heart illness like smoking, obesity, diabetes, high cholesterol, and hypertension.

* Blood thinner intakes like Jantoven, Warfarin, and Coumadin.

Side effects

The most common side effects that a patient would feel include anemia, infection, thrombocytopenia, cytopenia, neutropenia, and bruise. Others may also experience skin malignant neoplasm, malignant neoplasm, hematuria, gastrointestinal bleeding and subdural hematoma.


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  1. February 13, 2018

    Imbruvica (ibrutinib) is a cancer medicine that interferes with the growth and spread of cancer cells in the body. Imbruvica is used to treat certain types of non-Hodgkin lymphoma, including mantle cell lymphoma (MCL), Waldenstrom’s macroglobulinemia, and chronic lymphocytic. It is a small molecule drug that binds permanently to a protein, Bruton’s tyrosine kinase, that is important in B cells.

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