Prolia is more commonly known by its generic name denosumab. It is a monoclonal antibody. Such kind is created to destroy and target certain cells in a patient’s body/ using such can help in protecting the healthy cells from any harm or damage.

The drug is used for the treatment of osteoporosis among women in their menopausal stage. These women are already at high risk to develop fracture of bones.

This is also used for increasing the bone mass in both men and women who are at risk to have a bone fracture which can be secondary to their need to receive cancer therapy.


The medicine comes with another brand name called Xgeva. It is also used for preventing fractures of the bone and other skeletal conditions in patients with tumors that already spread to the bone.

It is not recommended for use to patients with low calcium levels in blood or those with hypocalcemia.

This medicine is also not intended for use by pregnant women. It can cause potential harm to the fetus and may cause birth defects.

Prior to usage, it is also advisable to advise the doctor if you suffer from kidney disease, with a weakened immune system, intestinal surgery history or with thyroid surgery or hypoparathyroidism history. Allergies to latex should also be noted.

Way of use

Prolia is injectable under the skin of stomach, upper arm or upper thigh. Only registered health care practitioner shall administer the drug. It is only given usually twice each year or every 6 months interval.

During the treatment, the doctor may ask to increase vitamin D and calcium. Simply follow exactly what the doctor prescribed.

Side effects

Any allergic reaction should immediately seek medical attention. This may include rash, hives, itching, breathing difficulties, swelling of the face (tongue, lips or throat), and lightheadedness.

Signs of infections like chills, fever, painful urination, swelling, stomach pain (severe), and shortness of breath should also be informed by the physician.

Read more here.

  1. March 18, 2018

    Denosumab is a human monoclonal antibody for the treatment of osteoporosis, treatment-induced bone loss, metastases to bone, and giant cell tumor of bone. Denosumab is contraindicated in people with low blood calcium levels.Possible serious side effects include serious allergic reactions, low blood calcium, severe jaw bone problems, unusual thigh bone fractures, increased risk of broken bones.

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