Cytology. Severe dysplasia. Severe nuclear abnormality in immature basal cells. Keratinization or cornification may be present at surface or in isolated cells inside epithelium. Appearance on colposcopy. Acetowhite reaction. Dull, denser white, not shiny. Remains for longer time. Surface contour. Flat or raised. Margins. Sharp and distinct. Internal margins possibly present with LSIL. Vascular pattern. Coarse punctation and or mosaic. Wide intercapillary distance. Iodine uptake. Rejects iodine. A dense opaque acetowhite area with coarse mosaics. Disease progression: CIN3. CIN3 is characterized by severe dysplasia and carcinoma in situ and occurs in over two-thirds of the basal epithelium. CIN3, along with CIN2 lesions, are referred to as high-grade squamous intraepithelial lesions (HSIL). Cervix with CIN3. Image used with permission from Dr Alejandro Ortiz de la Peña.

Moderate cervical lesions — formally known as cervical intra-epithelial neoplasia grade 2 (CIN2) — are abnormal cells on the surface of the cervix.

CIN is not cervical cancer but does have the potential to progress to cancer. However, in many cases, therefore these cells may also return to normal or remain unchanged.

Right now, CIN2 is typically treated. But some studies have suggested that CIN2 lesions often regress completely without treatment, therefore, be simply monitored instead.

Some experts feel that approach could be especially important for younger women, since treating these lesions can pose a risk to future pregnancies.

However, in women younger than 30, the rate of regression rose to 60 percent, the researchers noted, while the rate of persistence was 23 percent, and the rate of progression was 11 percent.

Source:- WebMD

  1. September 17, 2018

    By experts opinion that is formally known as cervical intraepithelial neoplasia grade 2 (CIN2) — are abnormal cells on the surface of the cervix. CIN is not cervical cancer but does have the potential to progress to cancer. Thanks for the posting.

Write a comment:

*

Your email address will not be published.

The National Drug and Poison Information Center 1-800-222-1222

Copyright @ 2012-2019 All Rights Reserved. My Pharmacy Visit does not provide medical advice, diagnosis, or treatment.

Skip to toolbar