moebius syndrome

Moebius syndrome (also spelled Möbius) is a rare neurological disease that affects the muscles controlling eye movements and facial expressions. The signs that a person might be suffering from this condition are present as soon as the child is born. Weakness of the facial muscles and paralysis of the face are the most common symptoms of Moebius syndrome.

In medical history, there is evidence that the syndrome is inherited. For dominant genetic disorders to occur only one abnormal gene is enough for the disease to appear. There are families where more than one member of the family is affected, but this is rare. If multiple people in the family have the disease, it can be inherited in three ways: sex-linked, autosomal dominant, or autosomal recessive.

The rare disorder is characterized by lifetime facial paralysis, meaning that persons with the syndrome can’t smile, frown, often even blink or move their eyes. Unfortunately, there’s no diagnostic test for the syndrome at the moment. A diagnosis is based upon the detailed patient history, and a clinical evaluation.

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